Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 16/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19784007 | 0.89 | HDAC1 (0.42) | HDAC1ADRB2DRD2DRD1DRD4 | |
| SCHEMBL19784017 | 0.88 | ADRB2 (0.40) | HDAC1ADRB2DRD2DRD1DRD4 | |
| SCHEMBL19784429 | 0.86 | ADRB2 (0.39) | HDAC1ADRB2DRD2DRD1DRD4 | |
| SCHEMBL19784022 | 0.86 | ADRB2 (0.39) | HDAC1ADRB2DRD2DRD1DRD4 | |
| SCHEMBL24404494 | 0.85 | ADRB2 (0.43) | HDAC1ADRB2DRD2DRD1DRD4 | |
| SCHEMBL19784428 | 0.85 | ADRB2 (0.39) | HDAC1ADRB2DRD2DRD1DRD4 | |
| SCHEMBL19784365 | 0.85 | ADRB2 (0.42) | HDAC1ADRB2DRD2DRD1DRD4 | |
| SCHEMBL19784019 | 0.85 | ADRB2 (0.38) | HDAC1ADRB2DRD2DRD1DRD4 | |
| SCHEMBL24404532 | 0.85 | ADRB2 (0.39) | HDAC1ADRB2DRD2DRD1DRD4 | |
| SCHEMBL24404433 | 0.84 | ADRB2 (0.40) | HDAC1ADRB2DRD2DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011090-A1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-01-18 | — | — | WO | disclosed |