SCHEMBL19784979

SCHEMBL19784979

CO[SiH2]c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 8/20 0.58
TSHR P16473 1/20 0.52
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
NR1H2 P55055 1/20 0.46
BAX Q07812 1/20 0.46
MAOA P21397 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 1/20 0.43
CA4 P22748 1/20 0.42
HTT P42858 3/20 0.41
ALDH1A1 P00352 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
PGR P06401 1/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
GSTP1 P09211 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL50084 0.81
SCHEMBL2495989 0.77 LTA4H (0.63) LTA4HTSHRCA1CA2NR1H2
Diphenylether SCHEMBL28254838 0.75 LTA4H (0.80) LTA4HTSHRCA1CA2NR1H2
SCHEMBL3893562 0.75 LTA4H (0.92) LTA4HTSHRCA1CA2NR1H2
SCHEMBL9212518 0.75 LTA4H (0.92) LTA4HTSHRCA1CA2NR1H2
SCHEMBL435149 0.75 LTA4H (0.92) LTA4HTSHRCA1CA2NR1H2
SCHEMBL11576945 0.75 LTA4H (0.92) LTA4HTSHRCA1CA2NR1H2
SCHEMBL122719 0.75 LTA4H (0.92) LTA4HTSHRCA1CA2NR1H2
SCHEMBL22129853 0.75 LTA4H (0.92) LTA4HTSHRCA1CA2NR1H2
SCHEMBL1930164 0.75 LTA4H (0.60) LTA4HTSHRCA1CA2NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3484896-B1 SILOXANE MONOMERS, THEIR POLYMERIZATION AND USES THEREOF INKRON OY (FI) 2023-11-22 EP disclosed
WO-2018011475-A1 SILOXANE MONOMERS, THEIR POLYMERIZATION AND USES THEREOF INKRON OY (FI) 2018-01-18 WO disclosed