SCHEMBL19785016

SCHEMBL19785016

O[SiH2]c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.57
TSHR P16473 1/20 0.57
NR1H2 P55055 1/20 0.56
BAX Q07812 1/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
MAOA P21397 1/20 0.50
PARP10 Q53GL7 1/20 0.47
SRD5A2 P31213 1/20 0.45
FFAR1 O14842 1/20 0.42
IDH1 O75874 1/20 0.42
GSTP1 P09211 1/20 0.42
SOS1 Q07889 1/20 0.42
CA9 Q16790 1/20 0.42
PLA2G2A P14555 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2495989 0.80 LTA4H (0.63) LTA4HTSHRNR1H2BAXCA1
SCHEMBL11576945 0.79 LTA4H (0.92) LTA4HTSHRNR1H2BAXCA1
SCHEMBL9212518 0.79 LTA4H (0.92) LTA4HTSHRNR1H2BAXCA1
SCHEMBL22129853 0.79 LTA4H (0.92) LTA4HTSHRNR1H2BAXCA1
SCHEMBL3893562 0.79 LTA4H (0.92) LTA4HTSHRNR1H2BAXCA1
SCHEMBL122719 0.79 LTA4H (0.92) LTA4HTSHRNR1H2BAXCA1
SCHEMBL435149 0.79 LTA4H (0.92) LTA4HTSHRNR1H2BAXCA1
SCHEMBL1930164 0.78 LTA4H (0.60) LTA4HTSHRNR1H2BAXCA1
Diphenylether SCHEMBL787081 0.76 LTA4H (0.75) LTA4HTSHRNR1H2BAXCA1
SCHEMBL619645 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3484896-B1 SILOXANE MONOMERS, THEIR POLYMERIZATION AND USES THEREOF INKRON OY (FI) 2023-11-22 EP disclosed
EP-3271366-B1 HIGH-RI SILOXANE MONOMERS, THEIR POLYMERIZATION AND USE INKRON OY (FI) 2020-10-14 EP disclosed
WO-2018011475-A1 SILOXANE MONOMERS, THEIR POLYMERIZATION AND USES THEREOF INKRON OY (FI) 2018-01-18 WO disclosed