Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GALK1 | P51570 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16688110 | 0.93 | ESR2 (0.59) | ESR2CYP1A2CSNK2A1NPC1RAB9A | |
| SCHEMBL6436155 | 0.93 | ESR2 (0.59) | ESR2CYP1A2CSNK2A1NPC1RAB9A | |
| SCHEMBL24781142 | 0.89 | ESR2 (0.55) | ESR2CYP1A2CSNK2A1NPC1RAB9A | |
| SCHEMBL24406604 | 0.86 | MAPK1 (0.52) | ESR2CYP1A2CSNK2A1NPC1RAB9A | |
| SCHEMBL23446197 | 0.84 | MAPK1 (0.50) | ESR2CYP1A2CSNK2A1NPC1RAB9A | |
| SCHEMBL29493845 | 0.82 | AHR (0.74) | ESR2CYP1A2MEN1LMNAKMT2A | |
| SCHEMBL1443418 | 0.82 | AHR (0.74) | ESR2CYP1A2MEN1LMNAKMT2A | |
| SCHEMBL7465630 | 0.82 | ESR2 (0.48) | ESR2CYP1A2CSNK2A1NPC1RAB9A | |
| SCHEMBL29211652 | 0.82 | ESR2 (0.48) | ESR2CYP1A2CSNK2A1NPC1RAB9A | |
| SCHEMBL27850823 | 0.82 | ESR2 (0.48) | ESR2CYP1A2CSNK2A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246415-B2 | Process for preparing carbazoles | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-04-02 | — | — | US | disclosed |
| WO-2018013067-A1 | PROCESS FOR PREPARING CARBAZOLES | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246415-B2 | Process for preparing carbazoles | DCLK2, DCLK1, PDCD2L | ESR2 3209/4885CYP1A2 255/4885CSNK2A1 750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.