SCHEMBL29211652

SCHEMBL29211652

Clc1cc(-c2ccc(-c3ccccc3)cc2)ccc1-c1ncccn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.48
CYP1A2 P05177 1/20 0.40
CSNK2A1 P68400 2/20 0.40
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
NPSR1 Q6W5P4 3/20 0.39
TP53 P04637 3/20 0.39
HPGD P15428 2/20 0.39
TSHR P16473 2/20 0.39
MAP4K4 O95819 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPT P10636 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
APAF1 O14727 1/20 0.39
LMNA P02545 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27850823 1.00 ESR2 (0.48) ESR2CYP1A2CSNK2A1NPC1RAB9A
SCHEMBL30709000 0.89 CYP2A6 (0.44) ESR2CSNK2A1NPC1RAB9ASMN1; SMN2
SCHEMBL28871443 0.86 ESR2 (0.46) ESR2CYP1A2CSNK2A1NPC1RAB9A
SCHEMBL28395030 0.85 CSNK2A1 (0.47) ESR2CSNK2A1NPC1RAB9ASMN1; SMN2
SCHEMBL19785384 0.82 ESR2 (0.61) ESR2CYP1A2CSNK2A1NPC1RAB9A
SCHEMBL29134695 0.81 ESR2 (0.48) ESR2CYP1A2CSNK2A1NPC1RAB9A
SCHEMBL6436155 0.80 ESR2 (0.59) ESR2CYP1A2CSNK2A1NPC1RAB9A
SCHEMBL16688110 0.80 ESR2 (0.59) ESR2CYP1A2CSNK2A1NPC1RAB9A
SCHEMBL29134684 0.77 ESR2 (0.44) ESR2NPC1RAB9ANPSR1TP53
SCHEMBL22379975 0.77 GRM5 (0.44) ESR2NPC1RAB9ASMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112110896-B Organic electroluminescent material and application thereof 北京鼎材科技有限公司 2024-02-09 CN disclosed