Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 19/20 | 0.51 |
| ▸ | CD274 | Q9NZQ7 | 19/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19785839 | 0.89 | PDCD1 (0.66) | PDCD1CD274KDR | |
| SCHEMBL19779691 | 0.87 | PDCD1 (0.52) | PDCD1CD274KDR | |
| SCHEMBL29893705 | 0.87 | PDCD1 (0.52) | PDCD1CD274KDR | |
| SCHEMBL23265382 | 0.85 | PDCD1 (0.50) | PDCD1CD274KDR | |
| SCHEMBL19785841 | 0.79 | PDCD1 (0.46) | PDCD1CD274KDR | |
| SCHEMBL19785961 | 0.78 | CD274 (0.51) | PDCD1CD274 | |
| SCHEMBL19779678 | 0.76 | PDCD1 (0.66) | PDCD1CD274KDR | |
| SCHEMBL29893697 | 0.76 | PDCD1 (0.66) | PDCD1CD274KDR | |
| SCHEMBL19785996 | 0.72 | CD274 (0.49) | PDCD1CD274KDR | |
| SCHEMBL18979729 | 0.71 | PDCD1 (0.73) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013789-A1 | HETEROCYCLIC COMPOUNDS AS IMMUNOMODULATORS | INCYTE CORPORATION (US) | 2018-01-18 | — | — | WO | disclosed |