Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19787506 | 1.00 | NR1H2 (0.38) | NR1H2ALDH1A1TSHRGPR119USP2 | |
| SCHEMBL30427255 | 0.89 | NR1H2 (0.42) | NR1H2ALDH1A1TSHRGPR119USP2 | |
| SCHEMBL29017250 | 0.89 | NR1H2 (0.42) | NR1H2ALDH1A1TSHRGPR119USP2 | |
| SCHEMBL22079229 | 0.89 | NR1H2 (0.42) | NR1H2ALDH1A1TSHRGPR119USP2 | |
| SCHEMBL14636624 | 0.89 | NR1H2 (0.42) | NR1H2ALDH1A1TSHRGPR119USP2 | |
| SCHEMBL14636625 | 0.89 | NR1H2 (0.42) | NR1H2ALDH1A1TSHRGPR119USP2 | |
| SCHEMBL15920678 | 0.89 | NR1H2 (0.42) | NR1H2ALDH1A1TSHRGPR119USP2 | |
| SCHEMBL20051537 | 0.89 | NR1H2 (0.42) | NR1H2ALDH1A1TSHRGPR119USP2 | |
| SCHEMBL22943928 | 0.86 | ALDH1A1 (0.37) | NR1H2ALDH1A1TSHRGPR119USP2 | |
| SCHEMBL19341343 | 0.86 | ALDH1A1 (0.37) | NR1H2ALDH1A1TSHRGPR119USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180015099-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180015099-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | NISCH, ABL1, PAICS | NR1H2 4746/4885ALDH1A1 664/4885TSHR 2818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.