Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9777486 | 0.82 | IDO1 (0.58) | NFE2L2IDO1PAMHTR2AMAOB | |
| SCHEMBL4863423 | 0.82 | IDO1 (0.58) | NFE2L2IDO1PAMHTR2AMAOB | |
| SCHEMBL115403 | 0.80 | NFE2L2 (0.54) | NFE2L2MAOBMEN1KMT2ALMNA | |
| SCHEMBL9800772 | 0.80 | NFE2L2 (0.54) | NFE2L2MAOBMEN1KMT2ALMNA | |
| SCHEMBL2875295 | 0.80 | NFE2L2 (0.54) | NFE2L2MAOBMEN1KMT2ALMNA | |
| SCHEMBL7766758 | 0.79 | MAOB (0.54) | MAOBMEN1KMT2ALMNAMAPT | |
| SCHEMBL4561527 | 0.79 | NFE2L2 (0.41) | NFE2L2IDO1PAMHTR2AMAOB | |
| SCHEMBL7873732 | 0.78 | NFE2L2 (0.52) | NFE2L2MAOBMEN1KMT2ALMNA | |
| SCHEMBL31414061 | 0.76 | IDO1 (0.48) | NFE2L2IDO1PAMHTR2AMAOB | |
| SCHEMBL476635 | 0.76 | NFE2L2 (0.50) | NFE2L2IDO1PAMHTR2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484842-B1 | HALOGEN-CONTAINING METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2023-05-03 | — | — | EP | disclosed |
| US-11020730-B2 | Halogen-containing metathesis catalysts and methods thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-01 | — | — | US | disclosed |
| US-20190314799-A1 | HALOGEN-CONTAINING METATHESIS CATALYSTS AND METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-10-17 | — | — | US | disclosed |
| WO-2018013943-A1 | HALOGEN-CONTAINING METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190314799-A1 | HALOGEN-CONTAINING METATHESIS CATALYSTS AND METHODS THEREOF | ZRANB2, SLC39A3, ZCCHC8 | NFE2L2 562/4885IDO1 1928/4885PAM 3430/4885 |
| US-11020730-B2 | Halogen-containing metathesis catalysts and methods thereof | ZRANB2, SLC39A3, ZCCHC8 | NFE2L2 562/4885IDO1 1928/4885PAM 3430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.