Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18388025 | 0.75 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL5686826 | 0.74 | — | — | |
| SCHEMBL7141375 | 0.74 | — | — | |
| SCHEMBL277863 | 0.72 | — | — | |
| Water SCHEMBL11312398 | 0.72 | — | — | |
| SCHEMBL13757276 | 0.70 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL4877987 | 0.69 | TSHR (0.35) | TSHRALDH1A1 | |
| Benzene SCHEMBL10352412 | 0.67 | CYP1A2 (0.33) | — | |
| SCHEMBL1242589 | 0.67 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL6533335 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981969-B2 | Imidazole derivatives and methods of use thereof for improving the pharmacokinetics of a drug | MERCK SHARP & DOHME CORP. (US) | 2018-05-29 | — | — | US | disclosed |
| US-9873671-B2 | Azepane derivatives and methods of treating hepatitis B infections | NOVIRA THERAPEUTICS, INC. (US) | 2018-01-23 | — | — | US | disclosed |