Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3486034 | 0.83 | FAAH (0.42) | FAAHCNR1CNR2LMNACHRM2 | |
| SCHEMBL21023233 | 0.83 | FAAH (0.42) | FAAHCNR1CNR2LMNACHRM2 | |
| SCHEMBL19443244 | 0.83 | FAAH (0.42) | FAAHCNR1CNR2LMNACHRM2 | |
| SCHEMBL18636465 | 0.82 | CYP19A1 (0.46) | SLC1A3SLC1A2LMNACYP19A1CHRM2 | |
| SCHEMBL15811732 | 0.81 | FAAH (0.34) | FAAHCNR1CNR2LMNACHRM2 | |
| SCHEMBL18274711 | 0.79 | — | — | |
| SCHEMBL15427306 | 0.79 | FAAH (0.51) | FAAHCNR1CNR2LMNACA1 | |
| SCHEMBL9830791 | 0.78 | FAAH (0.50) | FAAHCNR1CNR2SLC1A3SLC1A2 | |
| SCHEMBL20750933 | 0.78 | FAAH (0.39) | FAAHCNR1CNR2LMNAKDM4E | |
| SCHEMBL18823277 | 0.78 | FAAH (0.33) | FAAHCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872918-B2 | Hydroxyl-polymer-drug-protein conjugates | MERSANA THERAPEUTICS, INC. (US) | 2018-01-23 | — | — | US | disclosed |