Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 6/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 6/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18682734 | 0.85 | CCR1 (0.52) | PDE10ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL18500854 | 0.83 | CCR1 (0.30) | PDE10ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL18576848 | 0.81 | CYP2D6 (0.34) | HDAC6MAPT | |
| SCHEMBL25719539 | 0.78 | PDE10A (0.43) | PDE10ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL18648928 | 0.78 | TSHR (0.43) | PDE10ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL8269251 | 0.76 | DHFR (0.45) | PDE10ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL18772897 | 0.76 | PDE10A (0.44) | PDE10ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL18500836 | 0.76 | TSHR (0.31) | GABRA1GABRA5 | |
| SCHEMBL991122 | 0.75 | CCR1 (0.46) | PDE10ACCR1CCR5CCR8HDAC6 | |
| SCHEMBL19369541 | 0.74 | PDE10A (0.43) | PDE10ACCR1CCR5CCR8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9876173-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-01-23 | — | — | US | disclosed |