Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.61 |
| ▸ | CA2 | P00918 | 11/20 | 0.61 |
| ▸ | CA9 | Q16790 | 11/20 | 0.61 |
| ▸ | CA12 | O43570 | 6/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13219607 | 0.92 | CA1 (0.72) | CA1CA2CA9CA12CA14 | |
| SCHEMBL13815114 | 0.91 | CA1 (0.71) | CA1CA2CA9CA12CA14 | |
| SCHEMBL19426705 | 0.89 | CA9 (0.71) | CA1CA2CA9CA12CA14 | |
| SCHEMBL19788026 | 0.86 | CA9 (0.62) | CA1CA2CA9CA12CA14 | |
| SCHEMBL12185092 | 0.86 | CA9 (0.73) | CA1CA2CA9CA12CA14 | |
| SCHEMBL12231697 | 0.85 | CA9 (0.75) | CA1CA2CA9CA12CA14 | |
| SCHEMBL12678101 | 0.84 | CA9 (0.72) | CA1CA2CA9CA12CA14 | |
| SCHEMBL16158984 | 0.83 | CA9 (0.81) | CA1CA2CA9CA12CA14 | |
| SCHEMBL13915130 | 0.83 | CA9 (0.73) | CA1CA2CA9CA12CA14 | |
| SCHEMBL14032680 | 0.83 | CA9 (0.66) | CA1CA2CA9CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9874562-B2 | Zanamivir phosphonate congeners with anti-influenza activity and determining oseltamivir susceptibility of influenza viruses | ACADEMIA SINICA (TW) | 2018-01-23 | — | — | US | disclosed |