SCHEMBL19788092

SCHEMBL19788092

CCOCCC(C)(C[C@@H](Cc1ccc(-c2ccccc2)cc1)NC(=O)c1c[nH]nn1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MME P08473 19/20 0.51
ACE P12821 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19788049 0.92 MME (0.54) MMEACE
SCHEMBL19687833 0.91 MME (0.53) MMEACE
SCHEMBL15467353 0.91 MME (0.53) MMEACE
SCHEMBL19788111 0.90 MME (0.52) MMEACE
SCHEMBL19788048 0.89 MME (0.51) MMEACE
SCHEMBL11969744 0.87 MME (0.66) MMEACE
SCHEMBL15202178 0.87 MME (0.66) MMEACE
SCHEMBL19788089 0.86 MME (0.51) MMEACE
SCHEMBL26381316 0.86 MME (0.52) MME
SCHEMBL19687838 0.85 MME (0.54) MMEACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9873685-B2 Neprilysin inhibitors THERAVANCE BIOPHARMA R&D IP, LLC (US) 2018-01-23 US disclosed