Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 7/20 | 0.78 |
| ▸ | TPO | P07202 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14936245 | 0.88 | MPO (1.00) | MPOTPOGAAMAPK1KDM4E | |
| SCHEMBL14936759 | 0.87 | MPO (0.71) | MPOTPOGAAMAPK1KDM4E | |
| SCHEMBL14937141 | 0.86 | MPO (0.87) | MPOTPOGAAMAPK1KDM4E | |
| SCHEMBL14936986 | 0.86 | MPO (0.72) | MPOTPOGAAMAPK1KDM4E | |
| SCHEMBL14936162 | 0.85 | MPO (1.00) | MPOTPOGAAMAPK1KDM4E | |
| SCHEMBL14937034 | 0.85 | MPO (0.80) | MPOTPOGAAMAPK1KDM4E | |
| SCHEMBL14936753 | 0.85 | MPO (0.82) | MPOTPOGAAMAPK1KDM4E | |
| SCHEMBL14936613 | 0.85 | MPO (0.85) | MPOTPOGAAMAPK1KDM4E | |
| SCHEMBL14936368 | 0.85 | MPO (0.78) | MPOTPOGAAMAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL14936491 | 0.84 | MPO (0.98) | MPOTPOGAAMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9873673-B2 | 2-thiopyrimidinones | PFIZER INC. (US) | 2018-01-23 | — | — | US | disclosed |