Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.57 |
| ▸ | HRH2 | P25021 | 15/20 | 0.56 |
| ▸ | HRH1 | P35367 | 15/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1978873 | 1.00 | HRH3 (0.57) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL1978869 | 1.00 | HRH3 (0.57) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL1981459 | 0.86 | HRH3 (0.47) | HRH3HRH2HRH1 | |
| SCHEMBL14150224 | 0.83 | HRH3 (0.68) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL4491586 | 0.83 | HRH3 (0.68) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL1981461 | 0.81 | HRH3 (0.47) | HRH3MEN1 | |
| SCHEMBL4494406 | 0.81 | HRH3 (0.68) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL4684886 | 0.80 | HRH3 (0.66) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL1981428 | 0.79 | HRH3 (0.57) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL1981431 | 0.79 | HRH3 (0.57) | HRH3HRH2HRH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070252-A1 | AZABICYCLO[3.2.0]HEPT-6-YL DERIVATIVES AS ANTAGONISTS OF HISTAMINE H3 RECEPTOR | LES LABORATOIRES SERVIER (FR) | 2011-06-16 | — | — | WO | disclosed |