SCHEMBL19789327

SCHEMBL19789327

COC[C@H](C)n1cnc(C=O)c1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 3/20 0.34
BAZ2A Q9UIF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19789443 1.00 BRD4 (0.34) BRD4BAZ2A
SCHEMBL19789308 0.81 KDM5A (0.32)
SCHEMBL30268835 0.81 LMNA (0.41)
SCHEMBL30268892 0.80
SCHEMBL6369474 0.77 KDM5A (0.33)
SCHEMBL26803155 0.75 BRD4 (0.32) BRD4
SCHEMBL26803157 0.75 BRD4 (0.32) BRD4
SCHEMBL30268858 0.74
SCHEMBL30268929 0.74 KDM5A (0.52)
SCHEMBL30268898 0.73 PSEN1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3272754-A1 IMIDAZOPYRROLIDINONE COMPOUNDS Novartis AG (CH) 2018-01-24 EP disclosed