Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | SLC9A3 | P48764 | 2/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907495 | 0.79 | THRB (0.50) | FFAR4FFAR1RARARARBALDH1A1 | |
| SCHEMBL14062810 | 0.67 | TDP1 (0.44) | FFAR4FFAR1ALDH1A1PPARGKMT2A | |
| SCHEMBL14062855 | 0.67 | FFAR4 (0.38) | FFAR4FFAR1ALDH1A1FASNCTSA | |
| SCHEMBL16982149 | 0.66 | POLB (0.48) | FFAR4FFAR1RARARARBKMT2A | |
| SCHEMBL6224544 | 0.66 | APP (0.45) | FFAR4FASNGRM2 | |
| SCHEMBL30629210 | 0.66 | GSTP1 (0.57) | FFAR4FFAR1GRM2 | |
| SCHEMBL29097678 | 0.65 | GRM2 (0.43) | FASNGRM2ALOX5APFEN1 | |
| SCHEMBL22459796 | 0.65 | RARB (0.43) | FFAR4FFAR1RARARARBPRKAB2 | |
| SCHEMBL22459266 | 0.65 | RARB (0.43) | FFAR4FFAR1RARARARBPRKAB2 | |
| SCHEMBL23638836 | 0.65 | GRM2 (0.49) | FASNGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |