Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11961803 | 0.92 | ELANE (0.51) | ELANELMNAKMT2AATMCYP1A2 | |
| SCHEMBL17433306 | 0.92 | ELANE (0.51) | ELANELMNAKMT2AATMCYP1A2 | |
| SCHEMBL10014244 | 0.89 | ELANE (0.47) | ELANEKMT2AATMCYP1A2MAPT | |
| SCHEMBL19524167 | 0.88 | ELANE (0.55) | ELANELMNAKMT2AATMCYP1A2 | |
| SCHEMBL12073120 | 0.87 | ELANE (0.49) | ELANELMNAKMT2AATMCYP1A2 | |
| SCHEMBL13683846 | 0.87 | LMNA (0.57) | ELANELMNAKMT2AATMCYP1A2 | |
| SCHEMBL2604638 | 0.87 | ELANE (0.41) | ELANELMNAKMT2AATMCYP1A2 | |
| SCHEMBL12149171 | 0.86 | ELANE (0.39) | ELANELMNAKMT2AATMCYP1A2 | |
| SCHEMBL22078596 | 0.86 | ELANE (0.51) | ELANELMNAKMT2AATMCYP1A2 | |
| SCHEMBL11961798 | 0.85 | ELANE (0.46) | ELANELMNAKMT2AATMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |