⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11785351 | 0.77 | TSHR (0.31) | — | |
| SCHEMBL23733173 | 0.71 | CA12 (0.34) | — | |
| SCHEMBL198304 | 0.71 | CA12 (0.34) | — | |
| SCHEMBL9106733 | 0.69 | CA12 (0.33) | — | |
| SCHEMBL6553194 | 0.69 | POLB (0.35) | — | |
| SCHEMBL317539 | 0.69 | CA12 (0.38) | — | |
| SCHEMBL28507221 | 0.67 | GSK3B (0.31) | — | |
| SCHEMBL8500805 | 0.67 | TSHR (0.37) | — | |
| SCHEMBL727395 | 0.67 | TSHR (0.37) | — | |
| SCHEMBL887169 | 0.67 | NOTUM (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331884-A1 | ETHYLENE-COPOLYMERS AND CATALYST MIXTURE FOR MAKING ETHYLENE COPOLYMERS | ARLANXEO NETHERLANDS B.V. (NL) | 2023-10-19 | — | — | US | disclosed |
| US-11767376-B2 | Catalyst mixture | ARLANXEO NETHERLANDS B.V. (NL) | 2023-09-26 | — | — | US | disclosed |
| US-11578148-B2 | Metal complex comprising amidine and thiophene fused cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. | 2023-02-14 | — | — | US | disclosed |
| EP-3732183-B1 | METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands Bv (NL) | 2021-10-20 | — | — | EP | disclosed |
| WO-2021185737-A1 | ETHYLENE-COPOLYMERS AND CATALYST MIXTURE FOR MAKING ETHYLENE COPOLYMERS | ARLANXEO NETHERLANDS B.V. (NL) | 2021-09-23 | — | — | WO | disclosed |
| EP-3882283-A1 | ETHYLENE-COPOLYMERS AND CATALYST MIXTURE FOR MAKING ETHYLENE COPOLYMERS | Arlanxeo Netherlands B.V. (NL) | 2021-09-22 | — | — | EP | disclosed |
| US-20210087305-A1 | METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2021-03-25 | — | — | US | disclosed |
| EP-3334768-B1 | CATALYST SYSTEM | Arlanxeo Netherlands Bv (NL) | 2020-05-27 | — | — | EP | disclosed |
| WO-2020058267-A1 | CATALYST MIXTURE | ARLANXEO NETHERLANDS B.V. (NL) | 2020-03-26 | — | — | WO | disclosed |
| US-10472431-B2 | Metal complex comprising amidine and substituted cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. (NL) | 2019-11-12 | — | — | US | disclosed |
| EP-3194412-B1 | METAL COMPLEX COMPRISING AMIDINE AND SUBSTITUTED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands Bv (NL) | 2019-08-07 | — | — | EP | disclosed |
| US-10316113-B2 | Catalyst system | ARLANXEO NETHERLANDS B.V. (NL) | 2019-06-11 | — | — | US | disclosed |
| EP-3272761-A1 | METALL COMPLEX COMPRISING AMIDINE AND SUBSTITUTED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands B.V. (NL) | 2018-01-24 | — | — | EP | disclosed |