Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 2/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.40 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | MPL | P40238 | 7/20 | 0.39 |
| ▸ | CTRC | Q99895 | 2/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 2/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95762 | 0.84 | TNNI3 (0.49) | AURKBAURKATNNI3TNNT2TNNC1 | |
| SCHEMBL11527283 | 0.82 | TNNI3 (0.48) | AURKBAURKATNNI3TNNT2TNNC1 | |
| SCHEMBL11528724 | 0.80 | AURKA (0.40) | AURKBAURKATNNI3TNNT2TNNC1 | |
| SCHEMBL11231720 | 0.80 | AURKA (0.47) | AURKBAURKATNNI3TNNT2TNNC1 | |
| SCHEMBL30081118 | 0.80 | AURKA (0.47) | AURKBAURKATNNI3TNNT2TNNC1 | |
| SCHEMBL27678372 | 0.80 | AURKA (0.47) | AURKBAURKATNNI3TNNT2TNNC1 | |
| SCHEMBL15851419 | 0.78 | CYP1A2 (0.46) | AURKBAURKAMPLCTRCALDH1A1 | |
| SCHEMBL15489099 | 0.78 | MPL (0.46) | AURKBAURKATNNI3TNNT2TNNC1 | |
| SCHEMBL461763 | 0.77 | TNNI3 (0.42) | AURKBAURKATNNI3TNNT2TNNC1 | |
| SCHEMBL21113847 | 0.77 | TNNI3 (0.42) | AURKBAURKATNNI3TNNT2TNNC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107208145-A | Multiplex quantitative PCR | 端粒诊断公司 | 2017-09-26 | — | — | CN | disclosed |
| WO-2017027062-A1 | PROBES FOR RAPID AND SPECIFIC DETECTION OF MYCOBACTERIA | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-02-16 | — | — | WO | disclosed |
| EP-2330908-A1 | FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER | Georgetown University (US) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010019967-A1 | FLUORESCENT CDK INHIBITORS FOR TREATMENT OF CANCER | GEORGETOWN UNIVERSITY (US) | 2010-02-18 | — | — | WO | disclosed |