Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723350 | 0.74 | — | — | |
| SCHEMBL16289784 | 0.72 | — | — | |
| SCHEMBL1200558 | 0.68 | APP (0.46) | CYP1A2GRM5KCNH2 | |
| SCHEMBL1201321 | 0.67 | — | — | |
| SCHEMBL5050099 | 0.67 | — | — | |
| SCHEMBL4618243 | 0.67 | — | — | |
| SCHEMBL131953 | 0.67 | — | — | |
| SCHEMBL1977971 | 0.65 | KCNH2 (0.41) | CYP1A2GRM5KCNH2 | |
| SCHEMBL29856498 | 0.62 | CYP1A2 (0.44) | CYP1A2GRM5KCNH2 | |
| SCHEMBL944190 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013153535-A1 | TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-10-17 | — | — | WO | disclosed |
| WO-2011072064-A1 | S PIRO [CHROMAN - 4, 4 ' - IMIDAZOL] ONES AS BETA - SECRETASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2011-06-16 | — | — | WO | disclosed |