Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1978099 | 0.89 | HIF1A (0.44) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL1746875 | 0.87 | KDM4E (0.44) | KDM4EMAPK1MAPTTNFALDH1A1 | |
| SCHEMBL1977303 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1HPGDHSD17B10GRM5 | |
| SCHEMBL9639509 | 0.80 | GRM5 (0.49) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL3846786 | 0.79 | KDM4E (0.47) | KDM4EMAPK1MAPTTNFALDH1A1 | |
| SCHEMBL29882733 | 0.79 | KDM4E (0.47) | KDM4EMAPK1MAPTTNFALDH1A1 | |
| SCHEMBL2943749 | 0.79 | KDM4E (0.47) | KDM4EMAPK1MAPTTNFALDH1A1 | |
| SCHEMBL7515463 | 0.79 | MAPT (0.44) | KDM4EMAPK1MAPTALDH1A1HPGD | |
| SCHEMBL18356238 | 0.79 | KDM4E (0.47) | KDM4EMAPK1MAPTTNFALDH1A1 | |
| SCHEMBL7080994 | 0.79 | FDPS (0.54) | KDM4EMAPK1MAPTTNFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1352629-B1 | Use of a pyridine-dicarboxylic acid derivative or a salt thereof to stimulate or induce keratinic fiber growth and/or to prevent its loss | OREAL (FR) | 2011-06-22 | — | — | EP | claimed |
| EP-1352629-A1 | Use of a pyridine-dicarboxylic acid derivative or a salt thereof to stimulate or induce keratinic fiber growth and/or to prevent its loss | L'OREAL (FR) | 2003-10-15 | — | — | EP | claimed |
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | disclosed |