Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905525 | 0.80 | TAAR1 (0.52) | TAAR1KCNH2TMEM97SIGMAR1MAOA | |
| SCHEMBL9969447 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HTTRIPK1DAOKCNH2 | |
| SCHEMBL631580 | 0.75 | TAAR1 (0.58) | ALDH1A1DAOTAAR1SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL1585557 | 0.73 | TAAR1 (0.56) | ALDH1A1TAAR1SLC6A3SLC6A2KDM4E | |
| SCHEMBL15735957 | 0.72 | KCNH2 (0.39) | ALDH1A1HTTRIPK1DAOKCNH2 | |
| SCHEMBL16105820 | 0.72 | DAO (0.55) | ALDH1A1HTTDAOTAAR1MAOA | |
| SCHEMBL562364 | 0.72 | SLC6A2 (0.55) | ALDH1A1HTTRIPK1DAOTAAR1 | |
| SCHEMBL5981842 | 0.72 | TAAR1 (0.48) | ALDH1A1TAAR1SLC6A2HTR2AATM | |
| SCHEMBL895460 | 0.71 | CYP2D6 (0.49) | ALDH1A1HTTDAOTAAR1SLC6A3 | |
| SCHEMBL15787604 | 0.71 | SLC6A2 (0.49) | DAOTAAR1SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3272749-A1 | AMINO-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINECARBOXAMIDES AND THEIR USE AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE | Bayer Pharma Aktiengesellschaft (DE) | 2018-01-24 | — | — | EP | disclosed |