Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CHUK | O15111 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980773 | 0.86 | KDM4E (0.54) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1983604 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1980699 | 0.83 | KDM4E (0.50) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1980243 | 0.80 | CHUK (0.61) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1980167 | 0.80 | CHUK (0.57) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1978967 | 0.78 | PIM1 (0.61) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1979008 | 0.73 | ALDH1A1 (0.66) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL1980977 | 0.73 | ALDH1A1 (0.66) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL29391519 | 0.72 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL2597652 | 0.72 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070298-A1 | DI-SUBSTITUTED 9H-PYRIDO[3,4-B]INDOLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | WO | claimed |
| WO-2011070298-A1 | DI-SUBSTITUTED 9H-PYRIDO[3,4-B]INDOLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | WO | disclosed |
| WO-2011070298-A1 | DI-SUBSTITUTED 9H-PYRIDO[3,4-B]INDOLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | WO | disclosed |