Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 6/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 5/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667359 | 0.84 | KDM4E (0.65) | KDM4EF13A1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1027805 | 0.82 | SMN1; SMN2 (0.64) | KDM4ESMN1; SMN2ALDH1A1NPC1RAB9A | |
| SCHEMBL105520 | 0.81 | KDM4E (0.71) | KDM4EF13A1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL10137210 | 0.79 | SMN1; SMN2 (0.60) | KDM4EF13A1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL15359146 | 0.79 | ESRRG (0.54) | KDM4EF13A1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL11508578 | 0.78 | RXFP1 (0.54) | KDM4EF13A1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL16622768 | 0.78 | KDM4E (0.49) | KDM4EF13A1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL9799589 | 0.77 | GLA (0.50) | KDM4EF13A1SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL5186025 | 0.76 | KMT2A (0.57) | KDM4EF13A1CYP2C19CYP2D6GAA | |
| SCHEMBL20380008 | 0.76 | SMN1; SMN2 (0.59) | KDM4EF13A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2510023-A1 | PHOTOALIGNMENT MATERIALS HAVING IMPROVED ADHESION | Transitions Optical, Inc. (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071794-A1 | PHOTOALIGNMENT MATERIALS HAVING IMPROVED ADHESION | TRANSITIONS OPTICAL, INC. (US) | 2011-06-16 | — | — | WO | disclosed |