Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14335950 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1HDAC2HDAC8 | |
| SCHEMBL1027588 | 0.84 | HTT (0.66) | SMN1; SMN2RAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL424305 | 0.84 | KDM4E (0.65) | SMN1; SMN2RAB9ANPC1HDAC2HDAC8 | |
| SCHEMBL1027805 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL4575937 | 0.81 | SMN1; SMN2 (0.62) | SMN1; SMN2RAB9ANPC1HDAC2HDAC8 | |
| SCHEMBL105520 | 0.81 | KDM4E (0.71) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL424304 | 0.80 | HDAC2 (0.58) | SMN1; SMN2RAB9ANPC1HDAC2HDAC8 | |
| SCHEMBL1979285 | 0.79 | KDM4E (0.46) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL15359146 | 0.79 | ESRRG (0.54) | SMN1; SMN2RAB9ANPC1KDM4EALDH1A1 | |
| SCHEMBL334426 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2RAB9ANPC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951503-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-10 | — | — | US | disclosed |
| US-8951503-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-10 | — | — | US | disclosed |
| US-20130121925-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-16 | — | — | US | disclosed |
| US-20130121925-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-05-16 | — | — | US | disclosed |
| US-8394357-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-12 | — | — | US | disclosed |
| US-8394357-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120009126-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120009126-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-01-12 | — | — | US | disclosed |
| US-7968714-B2 | Optical determination of glucose utilizing boronic acid adducts | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-28 | — | — | US | disclosed |
| US-7968714-B2 | Optical determination of glucose utilizing boronic acid adducts | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-28 | — | — | US | disclosed |
| EP-2259061-A2 | Boronic acid derivatives | The Regents of The University of California (US) | 2010-12-08 | — | — | EP | disclosed |
| US-20090148956-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20090149656-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20090148956-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20090148344-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20090149656-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20090148344-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-7470420-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-12-30 | — | — | US | disclosed |
| US-7470420-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-12-30 | — | — | US | disclosed |
| WO-2007067743-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS-II | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130121925-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | NISCH, FOSB, BLVRB | SMN1; SMN2 804/4885RAB9A 2858/4885NPC1 4275/4885 |
| US-20090149656-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | NISCH, FOSB, BLVRB | SMN1; SMN2 804/4885RAB9A 2858/4885NPC1 4275/4885 |
| US-20120009126-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | NISCH, FOSB, BLVRB | SMN1; SMN2 804/4885RAB9A 2858/4885NPC1 4275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.