Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 5/20 | 0.48 |
| ▸ | CTSL | P07711 | 4/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.48 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19792935 | 0.88 | BCL2 (0.49) | BCL2CTSLCTSSCTSKCTSB | |
| SCHEMBL19801193 | 0.88 | LARS1 (0.62) | BCL2CTSLCTSSCTSKCTSB | |
| SCHEMBL31650940 | 0.88 | AAK1 (0.57) | BCL2CTSLCTSSCTSKCTSB | |
| SCHEMBL19792922 | 0.88 | AAK1 (0.57) | BCL2CTSLCTSSCTSKCTSB | |
| SCHEMBL18019117 | 0.87 | BCL2 (0.61) | BCL2CTSLCTSSCTSKCTSB | |
| SCHEMBL17977199 | 0.87 | BCL2 (0.48) | BCL2CTSLCTSSCTSKCTSB | |
| SCHEMBL28608883 | 0.87 | BCL2 (0.48) | BCL2CTSLCTSSCTSKCTSB | |
| SCHEMBL18019220 | 0.85 | LARS1 (0.65) | BCL2CTSLCTSSCTSKCTSB | |
| SCHEMBL28594310 | 0.83 | LARS1 (0.55) | BCL2LARS1AAK1MCL1 | |
| SCHEMBL31650941 | 0.83 | LARS1 (0.55) | BCL2LARS1AAK1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022696-A1 | NOVEL N-ACYL-ARYLSULFONAMIDE DERIVATIVES AS AMINOACYL-TRNA SYNTHETASE INHIBITORS | THE LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022696-A1 | NOVEL N-ACYL-ARYLSULFONAMIDE DERIVATIVES AS AMINOACYL-TRNA SYNTHETASE INHIBITORS | AARS1, GARS1, ASNS | BCL2 4465/4885CTSL 1183/4885CTSS 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.