Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 11/20 | 0.75 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.50 |
| ▸ | TARS1 | P26639 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19792914 | 0.86 | LARS1 (1.00) | LARS1AAK1TARS1 | |
| SCHEMBL19792918 | 0.85 | LARS1 (0.81) | LARS1TARS1 | |
| SCHEMBL18019112 | 0.85 | LARS1 (1.00) | LARS1TARS1 | |
| SCHEMBL19792916 | 0.84 | LARS1 (0.85) | LARS1TARS1 | |
| SCHEMBL19792911 | 0.84 | LARS1 (1.00) | LARS1AAK1TARS1 | |
| SCHEMBL18019194 | 0.84 | LARS1 (0.80) | LARS1TARS1 | |
| SCHEMBL18019129 | 0.81 | LARS1 (1.00) | LARS1TARS1 | |
| SCHEMBL18019181 | 0.81 | LARS1 (1.00) | LARS1AAK1TARS1 | |
| SCHEMBL19792915 | 0.81 | LARS1 (1.00) | LARS1TARS1 | |
| SCHEMBL19792913 | 0.79 | LARS1 (1.00) | LARS1TARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022696-A1 | NOVEL N-ACYL-ARYLSULFONAMIDE DERIVATIVES AS AMINOACYL-TRNA SYNTHETASE INHIBITORS | THE LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2018-01-25 | — | — | US | disclosed |
| US-20180022696-A1 | NOVEL N-ACYL-ARYLSULFONAMIDE DERIVATIVES AS AMINOACYL-TRNA SYNTHETASE INHIBITORS | THE LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022696-A1 | NOVEL N-ACYL-ARYLSULFONAMIDE DERIVATIVES AS AMINOACYL-TRNA SYNTHETASE INHIBITORS | AARS1, GARS1, ASNS | LARS1 72/4885AAK1 2180/4885TARS1 82/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.