Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 15/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.52 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1978967 | 0.83 | PIM1 (0.61) | PIM1MAPTPIM3PIM2ACHE | |
| SCHEMBL1980671 | 0.79 | PIM1 (0.50) | PIM1MAPTPIM3PIM2ACHE | |
| SCHEMBL1979521 | 0.79 | PIM1 (0.50) | PIM1MAPTPIM3PIM2ACHE | |
| SCHEMBL1561284 | 0.79 | MAPT (0.81) | PIM1MAPTPIM3PIM2ACHE | |
| SCHEMBL1980500 | 0.78 | PIM1 (0.49) | PIM1MAPTPIM3PIM2ACHE | |
| SCHEMBL1981543 | 0.78 | PIM1 (0.49) | PIM1MAPTPIM3PIM2ACHE | |
| SCHEMBL1979823 | 0.78 | PIM1 (0.48) | PIM1MAPTPIM3PIM2ACHE | |
| SCHEMBL12666733 | 0.77 | CHEK1 (0.69) | PIM1MAPTPIM3PIM2ACHE | |
| SCHEMBL1987825 | 0.76 | PIM1 (0.53) | PIM1MAPTPIM3PIM2ACHE | |
| SCHEMBL473684 | 0.75 | CHEK1 (0.58) | PIM1MAPTPIM3PIM2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070298-A1 | DI-SUBSTITUTED 9H-PYRIDO[3,4-B]INDOLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | WO | disclosed |