Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.52 |
| ▸ | BACE2 | Q9Y5Z0 | 4/20 | 0.52 |
| ▸ | CTSD | P07339 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18293548 | 0.94 | ENPEP (0.48) | BACE1BACE2CTSDPTPN1ENPEP | |
| SCHEMBL5194261 | 0.91 | ENPEP (0.55) | BACE1BACE2CTSDENPEP | |
| SCHEMBL31089740 | 0.91 | ENPEP (0.55) | BACE1BACE2CTSDENPEP | |
| SCHEMBL31315589 | 0.88 | BACE1 (0.47) | BACE1BACE2CTSDENPEP | |
| SCHEMBL29904046 | 0.88 | BACE1 (0.51) | BACE1BACE2CTSDENPEP | |
| SCHEMBL1674822 | 0.87 | BACE1 (0.47) | BACE1BACE2CTSDPTPN1ENPEP | |
| SCHEMBL29873747 | 0.87 | ENPEP (0.52) | BACE1BACE2CTSDENPEP | |
| SCHEMBL28605707 | 0.87 | BACE1 (0.47) | BACE1BACE2CTSDPTPN1ENPEP | |
| SCHEMBL14093759 | 0.87 | BACE1 (0.53) | BACE1BACE2CTSD | |
| SCHEMBL31468688 | 0.87 | BACE1 (0.46) | BACE1BACE2CTSDENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3430031-B1 | PEPTIDES WITH ANTI-CANCER ACTIVITY | IDP DISCOVERY PHARMA S L (ES) | 2021-10-20 | — | — | EP | disclosed |
| EP-3430031-A1 | PEPTIDES WITH ANTI-CANCER ACTIVITY | IDP Discovery Pharma, S.L. (ES) | 2019-01-23 | — | — | EP | disclosed |
| EP-3400445-A1 | METHOD OF IDENTIFYING NOVEL PROTEIN AGGREGATION INHIBITORS BASED ON CHEMICAL KINETICS | Cambridge Enterprise Limited (GB) | 2018-11-14 | — | — | EP | disclosed |
| WO-2017157990-A1 | PEPTIDES WITH ANTI-CANCER ACTIVITY | IDP DISCOVERY PHARMA, S.L. (ES) | 2017-09-21 | — | — | WO | disclosed |
| WO-2017118841-A1 | METHOD OF IDENTIFYING NOVEL PROTEIN AGGREGATION INHIBITORS BASED ON CHEMICAL KINETICS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2017-07-13 | — | — | WO | disclosed |
| WO-2012024784-A1 | CELL-PROTECTIVE PEPTIDES AND USES THEREOF | UNIVERSITY OF TORONTO (CA) | 2012-03-01 | — | — | WO | disclosed |