Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 11/20 | 0.39 |
| ▸ | CES1 | P23141 | 10/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979467 | 1.00 | CES2 (0.39) | CES2CES1RAB9ALMNAMAPT | |
| SCHEMBL1704443 | 0.71 | CES2 (0.35) | CES2CES1LMNAALDH1A1 | |
| SCHEMBL1704378 | 0.71 | CNR2 (0.36) | CES2CES1ALDH1A1 | |
| SCHEMBL23917942 | 0.64 | — | — | |
| Benzil SCHEMBL8189065 | 0.63 | CES2 (0.70) | CES2CES1RAB9ALMNAMAPT | |
| Benzil SCHEMBL4832229 | 0.62 | CES2 (0.88) | CES2CES1RAB9ALMNAMAPT | |
| Benzil SCHEMBL27655380 | 0.62 | CES2 (0.88) | CES2CES1RAB9ALMNAMAPT | |
| SCHEMBL4625269 | 0.62 | CES2 (0.59) | CES2CES1RAB9ALMNAMAPT | |
| Benzil SCHEMBL9517636 | 0.61 | CES2 (1.00) | CES2CES1RAB9ALMNAMAPT | |
| Benzil SCHEMBL66 | 0.61 | CES2 (1.00) | CES2CES1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336114-A1 | Process for the synthesis of L-3,4 dihydroxy-6-[18F]fluoro-phenylalanine and 2-[18F]Fluor-L-tyrosine and their alpha-methylated derivatives starting from a precursor | Forschungszentrum Jülich GmbH (DE) | 2011-06-22 | — | — | EP | disclosed |