Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7430669 | 0.86 | TP53 (0.33) | TP53 | |
| SCHEMBL19138932 | 0.80 | TP53 (0.36) | TP53 | |
| SCHEMBL7939966 | 0.79 | POLB (0.36) | TP53 | |
| SCHEMBL14910081 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL14910257 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL14909609 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL14909893 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL14910256 | 0.79 | TSHR (0.30) | — | |
| SCHEMBL14910117 | 0.77 | RNPEP (0.33) | — | |
| SCHEMBL15611299 | 0.77 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011071716-A1 | HETEROCYCLIC COMPOUNDS CONTAINING AN INDOLE CORE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-16 | — | — | WO | disclosed |
| WO-2011071725-A1 | HETEROCYCLIC COMPOUNDS CONTAINING A PYRROLOPYRIDINE OR BENZIMIDAZOLE CORE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-06-16 | — | — | WO | disclosed |