Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 5/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29714768 | 0.91 | ALDH1A1 (0.81) | ALDH1A1LMNACYP3A4HSD17B10TSHR | |
| SCHEMBL29832337 | 0.91 | ALDH1A1 (0.81) | ALDH1A1LMNACYP3A4HSD17B10TSHR | |
| SCHEMBL29932757 | 0.91 | ALDH1A1 (0.81) | ALDH1A1LMNACYP3A4HSD17B10TSHR | |
| SCHEMBL110764 | 0.91 | ALDH1A1 (0.81) | ALDH1A1LMNACYP3A4HSD17B10TSHR | |
| SCHEMBL10349490 | 0.90 | ALDH1A1 (0.68) | ALDH1A1LMNACYP3A4HSD17B10TSHR | |
| SCHEMBL30392171 | 0.90 | ALDH1A1 (0.79) | ALDH1A1LMNACYP3A4HSD17B10TSHR | |
| SCHEMBL19758999 | 0.89 | ALDH1A1 (0.73) | ALDH1A1LMNACYP3A4HSD17B10TSHR | |
| SCHEMBL20924147 | 0.88 | ALDH1A1 (0.77) | ALDH1A1LMNACYP3A4HSD17B10TSHR | |
| SCHEMBL20961813 | 0.88 | ALDH1A1 (0.65) | ALDH1A1LMNACYP3A4HSD17B10TSHR | |
| SCHEMBL28777743 | 0.88 | ALDH1A1 (0.68) | ALDH1A1LMNACYP3A4HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022693-A1 | COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-01-25 | — | — | US | disclosed |
| US-20180022693-A1 | COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022693-A1 | COMPOUNDS | ERCC4, NQO1, ERCC5 | ALDH1A1 981/4885LMNA 2017/4885CYP3A4 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.