Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3365329 | 0.82 | HTT (0.46) | HTTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL3365324 | 0.82 | HTT (0.46) | HTTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL3365331 | 0.82 | HTT (0.46) | HTTALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL18373760 | 0.74 | CES2 (0.47) | HTTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL6689522 | 0.73 | KDM4E (0.46) | HTTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL6689526 | 0.73 | KDM4E (0.46) | HTTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL6689518 | 0.73 | KDM4E (0.46) | HTTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL3929731 | 0.71 | MAPK1 (0.43) | HTTALDH1A1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL3929729 | 0.71 | MAPK1 (0.43) | HTTALDH1A1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL782544 | 0.71 | IDO1 (0.49) | HTTALDH1A1LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180022693-A1 | COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180022693-A1 | COMPOUNDS | ERCC4, NQO1, ERCC5 | HTT 3217/4885ALDH1A1 981/4885LMNA 2017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.