Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3797356 | 0.84 | SIGMAR1 (0.56) | SIGMAR1NFKB1CA12CA1CA2 | |
| SCHEMBL24727705 | 0.81 | SIGMAR1 (0.40) | SIGMAR1 | |
| SCHEMBL24344783 | 0.79 | SIGMAR1 (0.43) | SIGMAR1NFKB1 | |
| SCHEMBL134072 | 0.78 | — | — | |
| SCHEMBL20090519 | 0.78 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL131735 | 0.76 | SIGMAR1 (0.76) | SIGMAR1NFKB1CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL23123533 | 0.76 | — | — | |
| SCHEMBL129839 | 0.76 | — | — | |
| SCHEMBL919889 | 0.74 | — | — | |
| SCHEMBL11719181 | 0.74 | SIGMAR1 (0.46) | SIGMAR1NFKB1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018014855-A1 | MULTISPECIFIC ANTIGEN BINDING PROTEINS AND METHODS OF USE THEREOF | NANJING LEGEND BIOTECH CO., LTD. (CN) | 2018-01-25 | — | — | WO | disclosed |
| WO-2018014260-A1 | MULTISPECIFIC ANTIGEN BINDING PROTEINS AND METHODS OF USE THEREOF | NANJING LEGEND BIOTECH CO., LTD. (CN) | 2018-01-25 | — | — | WO | disclosed |