Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.68 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983095 | 1.00 | HRH3 (0.68) | HRH3PARP10PARP15PARP2MAOB | |
| SCHEMBL1976489 | 0.89 | HRH3 (0.59) | HRH3PARP10PARP15PARP2MAOB | |
| SCHEMBL1976491 | 0.89 | HRH3 (0.59) | HRH3PARP10PARP15PARP2MAOB | |
| SCHEMBL1976486 | 0.89 | HRH3 (0.59) | HRH3PARP10PARP15PARP2MAOB | |
| SCHEMBL1976942 | 0.89 | HRH3 (0.73) | HRH3PARP10PARP15PARP2MAOB | |
| SCHEMBL1976941 | 0.89 | HRH3 (0.73) | HRH3PARP10PARP15PARP2MAOB | |
| SCHEMBL1976944 | 0.89 | HRH3 (0.73) | HRH3PARP10PARP15PARP2MAOB | |
| Hydrochloric Acid SCHEMBL13583122 | 0.88 | HRH3 (0.58) | HRH3PARP10PARP15PARP2MAOB | |
| Hydrochloric Acid SCHEMBL13583125 | 0.88 | HRH3 (0.58) | HRH3PARP10PARP15PARP2MAOB | |
| Hydrochloric Acid SCHEMBL13583120 | 0.88 | HRH3 (0.58) | HRH3PARP10PARP15PARP2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070251-A1 | NOVEL HEXAHYDROCYCLOPENTA[B]PYRROL DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-06-16 | — | — | WO | disclosed |