Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.73 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.52 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.52 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1976944 | 1.00 | HRH3 (0.73) | HRH3PARP10PARP15PARP2HRH2 | |
| SCHEMBL1976941 | 1.00 | HRH3 (0.73) | HRH3PARP10PARP15PARP2HRH2 | |
| SCHEMBL1979837 | 0.89 | HRH3 (0.68) | HRH3PARP10PARP15PARP2HRH2 | |
| SCHEMBL1983095 | 0.89 | HRH3 (0.68) | HRH3PARP10PARP15PARP2HRH2 | |
| SCHEMBL1981435 | 0.89 | HRH3 (0.57) | HRH3HRH2HRH1MAOBTBXAS1 | |
| SCHEMBL1981431 | 0.89 | HRH3 (0.57) | HRH3HRH2HRH1MAOBTBXAS1 | |
| SCHEMBL1981428 | 0.89 | HRH3 (0.57) | HRH3HRH2HRH1MAOBTBXAS1 | |
| SCHEMBL14152810 | 0.85 | HRH3 (1.00) | HRH3PARP10PARP15PARP2HRH2 | |
| SCHEMBL13570581 | 0.85 | HRH3 (1.00) | HRH3PARP10PARP15PARP2HRH2 | |
| SCHEMBL14152811 | 0.85 | HRH3 (1.00) | HRH3PARP10PARP15PARP2HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070252-A1 | AZABICYCLO[3.2.0]HEPT-6-YL DERIVATIVES AS ANTAGONISTS OF HISTAMINE H3 RECEPTOR | LES LABORATOIRES SERVIER (FR) | 2011-06-16 | — | — | WO | disclosed |