Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 5/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM6 | O15303 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344586 | 1.00 | SLC7A5 (0.41) | SLC7A5GRIK1PTGS1SLC7A11SLC1A1 | |
| SCHEMBL31207001 | 1.00 | SLC7A5 (0.41) | SLC7A5GRIK1PTGS1SLC7A11SLC1A1 | |
| SCHEMBL11971354 | 1.00 | SLC7A5 (0.41) | SLC7A5GRIK1PTGS1SLC7A11SLC1A1 | |
| SCHEMBL25661123 | 0.83 | SLC1A2 (0.42) | SLC7A5GRIK1PTGS1SLC7A11SLC1A1 | |
| SCHEMBL18788848 | 0.83 | SLC1A2 (0.42) | SLC7A5GRIK1PTGS1SLC7A11SLC1A1 | |
| SCHEMBL4551676 | 0.80 | SLC7A5 (0.43) | SLC7A5GRIK1PTGS1SLC7A11SLC1A1 | |
| SCHEMBL25660444 | 0.80 | SLC7A5 (0.43) | SLC7A5GRIK1PTGS1SLC7A11SLC1A1 | |
| SCHEMBL1236556 | 0.79 | SLC7A5 (0.46) | SLC7A5GRIK1PTGS1SLC7A11SLC1A1 | |
| SCHEMBL935820 | 0.79 | SLC7A5 (0.46) | SLC7A5GRIK1PTGS1SLC7A11SLC1A1 | |
| SCHEMBL31215074 | 0.79 | SLC7A5 (0.46) | SLC7A5GRIK1PTGS1SLC7A11SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005538-A | Method for synthesizing 4, 5-dihydroxyleucine derivative | 内蒙古大学 | 2024-05-10 | — | — | CN | claimed |
| US-20240082416-A1 | AMATOXIN ANALOGS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-03-14 | — | — | US | claimed |
| EP-4259643-A1 | AMATOXIN ANALOGS AND USES THEREOF | The University of British Columbia (CA) | 2023-10-18 | — | — | EP | claimed |
| WO-2022120476-A1 | AMATOXIN ANALOGS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-06-16 | — | — | WO | claimed |
| WO-2004021981-A2 | METHODS FOR THE PREPARATION OF β-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2004-03-18 | — | — | WO | claimed |
| US-20030113882-A1 | Methods for the preparation of beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-06-19 | — | — | US | claimed |
| CN-118005538-A | Method for synthesizing 4, 5-dihydroxyleucine derivative | 内蒙古大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-118005538-A | Method for synthesizing 4, 5-dihydroxyleucine derivative | 内蒙古大学 | 2024-05-10 | — | — | CN | disclosed |
| US-20240082416-A1 | AMATOXIN ANALOGS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-03-14 | — | — | US | disclosed |
| EP-4259643-A1 | AMATOXIN ANALOGS AND USES THEREOF | The University of British Columbia (CA) | 2023-10-18 | — | — | EP | disclosed |
| WO-2022120476-A1 | AMATOXIN ANALOGS AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-06-16 | — | — | WO | disclosed |
| US-8569452-B2 | Preparation of phalloidin and its derivatives | AMERICAN PEPTIDE COMPANY, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| WO-2013139993-A1 | PEPTIDE-BASED F-ACTIN AFFINITY MATRIX | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-09-26 | — | — | WO | disclosed |
| US-7964702-B2 | Phalloidin derivatives and methods for their synthesis | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-06-21 | — | — | US | disclosed |
| US-7452701-B2 | Methods for the preparation of β-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-11-18 | — | — | US | disclosed |
| US-20070275886-A1 | Phalloidin derivatives and methods for their synthesis | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2007-11-29 | — | — | US | disclosed |
| WO-2004021981-A2 | METHODS FOR THE PREPARATION OF β-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2004-03-18 | — | — | WO | disclosed |
| US-20030113882-A1 | Methods for the preparation of beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-06-19 | — | — | US | disclosed |
| WO-1998031380-A1 | PHALLOIDIN DERIVATIVES AND ANALOGS TO TREAT CONGESTIVE HEART FAILURE | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1998-07-23 | — | — | WO | disclosed |
| EP-0308983-A2 | NMR imaging with Mn(II) coordination compositions | SALUTAR, INC. (US) | 1989-03-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240082416-A1 | AMATOXIN ANALOGS AND USES THEREOF | VIP, MTX1, APLNR | SLC7A5 184/4885GRIK1 4127/4885PTGS1 3132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.