SCHEMBL1979909

SCHEMBL1979909

CC(C)(C)c1ccc(C=Cc2ccc(Br)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.53
RAB9A P51151 4/20 0.50
ALDH1A1 P00352 3/20 0.50
HPGD P15428 3/20 0.50
CYP2C19 P33261 2/20 0.50
KDM4E B2RXH2 2/20 0.50
GPR183 P32249 1/20 0.47
TUBB4A P04350 1/20 0.44
TUBB P07437 1/20 0.44
TUBA3C P0DPH7 1/20 0.44
TUBA1B P68363 1/20 0.44
TUBA4A P68366 1/20 0.44
TUBB4B P68371 1/20 0.44
TUBB3 Q13509 1/20 0.44
TUBB2A Q13885 1/20 0.44
TUBB8 Q3ZCM7 1/20 0.44
TUBA3E Q6PEY2 1/20 0.44
TUBA1A Q71U36 1/20 0.44
TUBA1C Q9BQE3 1/20 0.44
TUBB6 Q9BUF5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1979907 1.00 CYP1A2 (0.53) CYP1A2RAB9AALDH1A1HPGDCYP2C19
SCHEMBL4624190 0.89 CYP1A2 (0.44) CYP1A2RAB9AALDH1A1HPGDCYP2C19
SCHEMBL992672 0.89 CYP1A2 (0.44) CYP1A2RAB9AALDH1A1HPGDCYP2C19
SCHEMBL801380 0.89 CYP1A2 (0.44) CYP1A2RAB9AALDH1A1HPGDCYP2C19
SCHEMBL18892919 0.89 CYP1A2 (0.44) CYP1A2RAB9AALDH1A1HPGDCYP2C19
SCHEMBL1825729 0.88 CYP1A2 (0.64) CYP1A2RAB9AALDH1A1HPGDKDM4E
SCHEMBL1825727 0.88 CYP1A2 (0.64) CYP1A2RAB9AALDH1A1HPGDKDM4E
SCHEMBL29145894 0.85 CYP1A2 (0.61) CYP1A2RAB9AALDH1A1HPGDKDM4E
SCHEMBL5758 0.85 TSHR (0.55) RAB9AALDH1A1HPGDTSHRHDAC1
SCHEMBL13045353 0.83 TSHR (0.47) CYP1A2RAB9AALDH1A1HPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8901542-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-02 US disclosed
US-20120235130-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-20 US disclosed
US-8193701-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-06-05 US disclosed
EP-1931634-B1 STILBENE DERIVATIVES, LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2011-11-09 EP disclosed
US-20110147729-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-7898171-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-03-01 US disclosed
US-20090146558-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-06-11 US disclosed
US-7476745-B2 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-13 US disclosed
US-7449578-B1 substituted phenanthroline compounds with high two photon absorption cross sections; [3,8-Bis-{4-[2-(4-tert-butylsulfanyl-phenylvinyl]-phenyl}-[1,10] phenanthroline THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2008-11-11 US disclosed
EP-1931634-A1 STILBENE DERIVATIVES, LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-06-18 EP disclosed
WO-2007043371-A1 STILBENE DERIVATIVES, LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-04-19 WO disclosed
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090146558-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device NR0B1, NR2E3, NR0B2 CYP1A2 123/4885RAB9A 2456/4885ALDH1A1 13/4885
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability NR0B1, TERB1, CYP1B1 CYP1A2 572/4885RAB9A 859/4885ALDH1A1 78/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.