SCHEMBL19799375

SCHEMBL19799375

CNc1ccc(NC(=O)c2ccccc2C(=O)O)c2ncccc12

nearest known ligand 0.73

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.73
TP53 P04637 1/20 0.73
MEN1 O00255 5/20 0.55
KDM4E B2RXH2 5/20 0.54
MAPT P10636 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
L3MBTL1 Q9Y468 2/20 0.51
RAB9A P51151 2/20 0.47
PLEC Q15149 1/20 0.47
KDR P35968 3/20 0.47
ALDH1A1 P00352 1/20 0.47
PABPC1 P11940 1/20 0.46
EIF4H Q15056 1/20 0.46
CYP1A2 P05177 1/20 0.45
NPC1 O15118 1/20 0.44
CKS1B P61024 1/20 0.44
GLO1 Q04760 1/20 0.44
SKP2 Q13309 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19799373 0.95 KMT2A (0.70) KMT2ATP53MEN1KDM4EMAPT
SCHEMBL23409200 0.85 KMT2A (0.73) KMT2ATP53MEN1KDM4EMAPT
SCHEMBL31307866 0.85 KMT2A (1.00) KMT2ATP53MEN1KDM4EMAPT
SCHEMBL23493914 0.85 KMT2A (1.00) KMT2ATP53MEN1KDM4EMAPT
SCHEMBL17552240 0.84 KMT2A (0.69) KMT2ATP53MEN1KDM4EMAPT
SCHEMBL29831045 0.84 KMT2A (0.69) KMT2ATP53MEN1KDM4EMAPT
SCHEMBL26266880 0.82 KMT2A (0.70) KMT2ATP53MEN1KDM4EMAPT
SCHEMBL23409195 0.82 KMT2A (0.66) KMT2ATP53MEN1KDM4EMAPT
SCHEMBL12172758 0.79 MAPT (0.75) KMT2ATP53MEN1KDM4EMAPT
SCHEMBL19799374 0.75 MEN1 (0.51) KMT2AMEN1L3MBTL1NPC1CKS1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10947345-B2 Varnish for photo alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2021-03-16 US disclosed
US-20180022874-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2018-01-25 US disclosed
US-20180022874-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2018-01-25 US disclosed