SCHEMBL23409200

SCHEMBL23409200

Nc1ccc(NC(=O)c2ccccc2C(=O)O)c2ncccc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.73
TP53 P04637 1/20 0.73
KDM4E B2RXH2 6/20 0.54
MAPT P10636 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
MEN1 O00255 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.51
PLEC Q15149 1/20 0.47
KDR P35968 2/20 0.47
PRKCI P41743 1/20 0.47
HSP90AA1 P07900 1/20 0.46
HSP90AB1 P08238 1/20 0.46
IDO1 P14902 1/20 0.46
PSMB5 P28074 1/20 0.46
CYP1A2 P05177 1/20 0.45
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
ALDH1A1 P00352 2/20 0.44
NAPRT Q6XQN6 1/20 0.44
HDAC1 Q13547 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23409195 0.90 KMT2A (0.66) KMT2ATP53KDM4EMAPTSMN1; SMN2
SCHEMBL31307866 0.85 KMT2A (1.00) KMT2ATP53KDM4EMAPTSMN1; SMN2
SCHEMBL23493914 0.85 KMT2A (1.00) KMT2ATP53KDM4EMAPTSMN1; SMN2
SCHEMBL19799375 0.85 KMT2A (0.73) KMT2ATP53KDM4EMAPTSMN1; SMN2
SCHEMBL26266880 0.82 KMT2A (0.70) KMT2ATP53KDM4EMAPTSMN1; SMN2
SCHEMBL19799373 0.82 KMT2A (0.70) KMT2ATP53KDM4EMAPTSMN1; SMN2
SCHEMBL29831045 0.81 KMT2A (0.69) KMT2ATP53KDM4EMAPTSMN1; SMN2
SCHEMBL17552240 0.81 KMT2A (0.69) KMT2ATP53KDM4EMAPTSMN1; SMN2
SCHEMBL12172758 0.79 MAPT (0.75) KMT2ATP53KDM4EMAPTSMN1; SMN2
SCHEMBL29848459 0.77 HSP90AA1 (0.59) KMT2AKDM4EMAPTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384204-B2 Varnish for photo alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2022-07-12 US disclosed
US-20210155755-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2021-05-27 US disclosed