SCHEMBL197996

SCHEMBL197996

C=CCOC(=O)C(=C)C.C=CN1CCCC1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.38
ALDH1A1 P00352 6/20 0.38
THRB P10828 1/20 0.36
CYP3A4 P08684 1/20 0.35
MAPT P10636 3/20 0.33
HSD17B10 Q99714 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
CACNA1B Q00975 1/20 0.30
APBA1 Q02410 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8921614 0.84
SCHEMBL4823985 0.84
SCHEMBL28226548 0.84 TSHR (0.50) TSHRALDH1A1THRBCYP3A4MAPT
SCHEMBL6269152 0.84
SCHEMBL1057516 0.84 TSHR (0.50) TSHRALDH1A1THRBCYP3A4MAPT
SCHEMBL22017 0.84
SCHEMBL5442968 0.82 THRB (0.42) TSHRALDH1A1THRBCA1CA2
Acetone SCHEMBL11804126 0.82 TSHR (0.48) TSHRALDH1A1THRBCYP3A4MAPT
Fluoride SCHEMBL8087473 0.82 TSHR (0.48) TSHRALDH1A1THRBCYP3A4MAPT
Ethylene SCHEMBL460398 0.82 TSHR (0.48) TSHRALDH1A1THRBCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106463710-B High capacity electrode 南达科他州评议委员会 2021-01-05 CN disclosed
EP-2364335-B1 METHODS OF MAKING THERMALLY RESISTANT MINERAL-FILLED POLYACETAL COMPOSITIONS DU PONT (US) 2014-08-27 EP disclosed
EP-1828308-B1 HIGH DENSITY POLYOXYMETHYLENE COMPOSITIONS DU PONT (US) 2012-01-04 EP disclosed
EP-2364335-A2 METHODS OF MAKING THERMALLY RESISTANT MINERAL-FILLED POLYACETAL COMPOSITIONS E. I. du Pont de Nemours and Company (US) 2011-09-14 EP disclosed
WO-2010065687-A2 METHODS OF MAKING THERMALLY RESISTANT MINERAL-FILLED POLYACETAL COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 WO disclosed
EP-1828308-A2 HIGH DENSITY POLYOXYMETHYLENE COMPOSITIONS E.I.Du pont de nemours and company (US) 2007-09-05 EP disclosed
WO-2006057975-A2 HIGH DENSITY POLYOXYMETHYLENE COMPOSITIONS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-06-01 WO disclosed
US-20060111473-A1 High density polyoxymethylene compositions E. I. DU PONT DE NEMOURS AND COMPANY 2006-05-25 US disclosed
EP-0672692-B1 Hybrid copolymers of nitrogenous graft copolymers with random nitrogenous copolymers, and methods for their preparation ROEHM ROHMAX HOLDING GMBH (DE) 2000-02-23 EP disclosed
EP-0393899-B1 Nitrogenous graft copolymers, hybrid copolymers of such graft copolymers with random nitrogenous copolymers, and methods for their preparation ROHM & HAAS (US) 1996-05-22 EP disclosed
EP-0672692-A2 Hybrid copolymers of nitrogenous graft copolymers with random nitrogenous copolymers, and methods for their preparation ROHM AND HAAS COMPANY (US) 1995-09-20 EP disclosed
US-5064547-A Lubricant compositions for metals containing dicarboxylic acids as a major constituent CENTURY LABORATORIES, INCOPORATED (US) 1991-11-12 US disclosed
EP-0393899-A2 Nitrogenous graft copolymers, hybrid copolymers of such graft copolymers with random nitrogenous copolymers, and methods for their preparation ROHM AND HAAS COMPANY (US) 1990-10-24 EP disclosed
US-4146489-A LUBRICANTS, DISPERSANTS ROHM AND HAAS COMPANY (US) 1979-03-27 US disclosed