Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 4/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13834402 | 1.00 | LTB4R (0.36) | LTB4RLTB4R2CA2ADRA2AKDM1A | |
| SCHEMBL1979997 | 1.00 | LTB4R (0.36) | LTB4RLTB4R2CA2ADRA2AKDM1A | |
| SCHEMBL6899058 | 1.00 | LTB4R (0.36) | LTB4RLTB4R2CA2ADRA2AKDM1A | |
| SCHEMBL13834521 | 0.87 | GRM7 (0.41) | CA2KDM1AKDM1B | |
| SCHEMBL6899490 | 0.87 | GRM7 (0.41) | CA2KDM1AKDM1B | |
| SCHEMBL1981577 | 0.80 | MAP3K14 (0.53) | LTB4RLTB4R2CA2 | |
| SCHEMBL13834604 | 0.80 | MAP3K14 (0.53) | LTB4RLTB4R2CA2 | |
| SCHEMBL6897674 | 0.80 | AKR1B1 (0.38) | LTB4RLTB4R2ADRA2A | |
| SCHEMBL6900318 | 0.80 | MAP3K14 (0.53) | LTB4RLTB4R2CA2 | |
| SCHEMBL29920414 | 0.80 | HCRTR2 (0.37) | LTB4RLTB4R2CA2ADRA2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509950-A1 | 5-AMINO- 4-HYDROXYPENTOYL AMIDES | Janssen R&D Ireland (IE) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011070131-A1 | 5-AMINO- 4-HYDROXYPENTOYL AMIDES | TIBOTEC PHARMACEUTICALS (IE) | 2011-06-16 | — | — | WO | disclosed |