Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 13/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1742407 | 0.84 | LCK (0.46) | LCKCA1CA2PI4KB | |
| SCHEMBL9915405 | 0.84 | LCK (0.45) | LCKCA1CA2PI4KB | |
| SCHEMBL13403561 | 0.83 | LCK (0.46) | LCKCA1CA2PI4KB | |
| SCHEMBL9529240 | 0.81 | CA1 (0.41) | LCKCA1CA2PI4KBALDH1A1 | |
| SCHEMBL25187541 | 0.81 | CA1 (0.41) | LCKCA1CA2PI4KB | |
| SCHEMBL29019241 | 0.80 | MEN1 (0.50) | LCKCA1CA2PI4KBMEN1 | |
| SCHEMBL150084 | 0.80 | LCK (0.58) | LCKCA1CA2PI4KB | |
| SCHEMBL5023750 | 0.76 | LCK (0.60) | LCKCA1CA2PI4KBMEN1 | |
| SCHEMBL24675957 | 0.76 | LCK (0.46) | LCKCA1CA2PI4KBMEN1 | |
| SCHEMBL23413232 | 0.76 | CA1 (0.44) | LCKCA1CA2PI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489234-B1 | MONOCYCLIC B-LACTAM-IRON CARRIER CONJUGATE, AND MANUFACTURING METHOD AND APPLICATION THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2020-03-18 | — | — | EP | disclosed |
| EP-3489234-A1 | MONOCYCLIC B-LACTAM-IRON CARRIER CONJUGATE, AND MANUFACTURING METHOD AND APPLICATION THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2019-05-29 | — | — | EP | disclosed |
| WO-2018014823-A1 | MONOCYCLIC Β-LACTAM-IRON CARRIER CONJUGATE, AND MANUFACTURING METHOD AND APPLICATION THEREOF | 中国科学院上海药物研究所 | 2018-01-25 | — | — | WO | disclosed |