Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 10/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24434747 | 0.85 | L3MBTL1 (0.47) | CA1CA2LCKPI4KBALDH1A1 | |
| SCHEMBL9915405 | 0.82 | LCK (0.45) | CA1CA2LCKPI4KB | |
| SCHEMBL19801577 | 0.81 | LCK (0.46) | CA1CA2LCKPI4KBALDH1A1 | |
| SCHEMBL13403561 | 0.81 | LCK (0.46) | CA1CA2LCKPI4KB | |
| SCHEMBL2174374 | 0.81 | LCK (0.52) | CA1CA2LCKPI4KBALDH1A1 | |
| SCHEMBL4257610 | 0.79 | CA1 (0.41) | CA1CA2LCKPI4KBALDH1A1 | |
| SCHEMBL25187541 | 0.79 | CA1 (0.41) | CA1CA2LCKPI4KB | |
| SCHEMBL24434742 | 0.77 | CA1 (0.42) | CA1CA2LCKPI4KBALDH1A1 | |
| SCHEMBL4261234 | 0.77 | CA1 (0.40) | CA1CA2LCKPI4KBALDH1A1 | |
| SCHEMBL4135543 | 0.76 | LCK (0.37) | CA1CA2LCKPI4KBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187500-B1 | MONOBACTAMS | THE UPJOHN COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |
| EP-0187500-A1 | Monobactams | THE UPJOHN COMPANY (US) | 1986-07-16 | — | — | EP | disclosed |