Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28233832 | 1.00 | AKR1B1 (0.36) | AKR1B1LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL11858560 | 0.86 | LMNA (0.43) | AKR1B1LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL28257916 | 0.86 | LMNA (0.43) | AKR1B1LMNAL3MBTL1TDP1PDE4A | |
| SCHEMBL2453623 | 0.76 | AKR1B1 (0.33) | AKR1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL5496629 | 0.76 | AKR1B1 (0.33) | AKR1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL23856034 | 0.76 | AKR1B1 (0.33) | AKR1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL28647875 | 0.76 | AKR1B1 (0.39) | AKR1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL112933 | 0.76 | AKR1B1 (0.39) | AKR1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL18383123 | 0.76 | AKR1B1 (0.33) | AKR1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL23856035 | 0.76 | AKR1B1 (0.33) | AKR1B1LMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115044645-A | Efficient construction of DNA libraries | 分析生物科学有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-108431233-B | Efficient construction of DNA libraries | 分析生物科学有限公司 | 2022-04-01 | — | — | CN | disclosed |
| US-10335372-B2 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases | Appelbaum, Jacob G. (US) | 2019-07-02 | — | — | US | disclosed |
| US-20170209376-A1 | COMPOSITIONS WITH MODIFIED NUCLEASES TARGETED TO VIRAL NUCLEIC ACIDS AND METHODS OF USE FOR PREVENTION AND TREATMENT OF VIRAL DISEASES | NANONASE, INC. | 2017-07-27 | — | — | US | disclosed |
| US-9592277-B2 | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases | AVIRID, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| CN-103068834-B | Phosphoramidites for reverse RNA synthesis | 坎姆根公司 | 2016-10-26 | — | — | CN | disclosed |
| US-8541569-B2 | Phosphoramidites for synthetic RNA in the reverse direction, efficient RNA synthesis and convenient introduction of 3'-end ligands, chromophores and modifications of synthetic RNA | CHEMGENES CORPORATION (US) | 2013-09-24 | — | — | US | disclosed |
| US-8461127-B2 | p27 and p21 in gene therapies | THE GENERAL HOSPITAL CORPORATION (US) | 2013-06-11 | — | — | US | disclosed |
| CN-103068834-A | Phosphoramidites for reverse RNA synthesis | CHEMGENES CORP | 2013-04-24 | — | — | CN | disclosed |
| US-20130004470-A1 | p27 AND p21 IN GENE THERAPIES | THE GENERAL HOSPITAL CORPORATION (US) | 2013-01-03 | — | — | US | disclosed |
| WO-2004012791-A2 | IMPROVED INJECTION SYSTEM | GENVEC, INC. (US) | 2004-02-12 | — | — | WO | disclosed |
| US-20030084465-A1 | Animal model of allergies | ARKANSAS, UNIVERSITY OF | 2003-05-01 | — | — | US | disclosed |
| EP-1269188-A2 | ONE-DIMENSIONAL ARRAYS ON OPTICAL FIBERS | Wisys Technology Foundation, Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6462191-B1 | DEOXOFLUORINATION OF FURANOSE; HEATING | AIR PRODUCTS AND CHEMICALS, INC. | 2002-10-08 | — | — | US | disclosed |
| US-20020006663-A1 | p27 and p21 in gene therapies | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-01-17 | — | — | US | disclosed |
| EP-1172369-A1 | Synthesis of 2-deoxy-2-fluoro-arabinose derivates | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-01-16 | — | — | EP | disclosed |
| WO-2001071316-A2 | ONE-DIMENSIONAL ARRAYS ON OPTICAL FIBERS | WISYS TECHNOLOGY FOUNDATION, INC. (US) | 2001-09-27 | — | — | WO | disclosed |
| WO-2001066699-A2 | P27 AND P21 IN GENE THERAPIES | THE GENERAL HOSPITAL CORPORATION (US) | 2001-09-13 | — | — | WO | disclosed |
| WO-2001054744-A1 | TRANSDERMAL THERMAL POLYMERIZATION | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-08-02 | — | — | WO | disclosed |
| WO-2000051647-A2 | ANIMAL MODEL OF ALLERGIES | MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY (US) | 2000-09-08 | — | — | WO | disclosed |