SCHEMBL19804102

SCHEMBL19804102

C=C(C)C(=O)OCCOc1cc(CO)ccc1-c1ccc(C)cc1F

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
FFAR4 Q5NUL3 2/20 0.37
GRM2 Q14416 1/20 0.35
HDAC1 Q13547 3/20 0.35
KDM1A O60341 2/20 0.35
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
TDP1 Q9NUW8 2/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
THRB P10828 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
KDM4E B2RXH2 1/20 0.32
FFAR1 O14842 1/20 0.32
GAA P10253 1/20 0.32
PPARG P37231 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19804289 0.91 GRM2 (0.36) CYP4F2CYP4A11FFAR4GRM2HDAC1
SCHEMBL19804109 0.89 CA1 (0.35) CYP4F2CYP4A11FFAR4HDAC1KDM1A
SCHEMBL19796328 0.88 CYP4F2 (0.41) CYP4F2CYP4A11TDP1POLBAPEX1
SCHEMBL19803992 0.86 FFAR4 (0.44) CYP4F2CYP4A11FFAR4CA1CA2
SCHEMBL19796365 0.86 CYP4F2 (0.37) CYP4F2CYP4A11FFAR4GRM2HDAC1
SCHEMBL19804606 0.85 SLC6A9 (0.40) CYP4F2CYP4A11FFAR4EGFR
SCHEMBL19804171 0.84 FFAR4 (0.42) FFAR4CA1CA2TDP1POLB
SCHEMBL19796788 0.82 RARB (0.46) CYP4F2CYP4A11THRBTSHR
SCHEMBL19804192 0.82 FEN1 (0.41) CYP4F2CYP4A11FFAR4KDM4EEGFR
SCHEMBL19804215 0.81 CA1 (0.35) CYP4F2CYP4A11FFAR4HDAC1KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180023001-A1 COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180023001-A1 COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, C1S, AP3D1 CYP4F2 2577/4885CYP4A11 1991/4885FFAR4 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.