SCHEMBL19804209

SCHEMBL19804209

C=CC(=O)OCc1cc(C)ccc1-c1ccc(CO)cc1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 6/20 0.42
FFAR1 O14842 6/20 0.42
PTGER4 P35408 1/20 0.38
MAP2K4 P45985 1/20 0.36
THRB P10828 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SRC P12931 1/20 0.33
BAZ2B Q9UIF8 1/20 0.33
BAZ2A Q9UIF9 1/20 0.33
RAB9A P51151 1/20 0.33
MAPK1 P28482 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALOX5 P09917 1/20 0.33
ERN1 O75460 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19804218 0.94 FFAR4 (0.43) FFAR4FFAR1PTGER4MAP2K4THRB
SCHEMBL19624542 0.92 FFAR4 (0.43) FFAR4FFAR1PTGER4MAP2K4THRB
SCHEMBL19624565 0.91 FFAR4 (0.44) FFAR4FFAR1THRBSMN1; SMN2
SCHEMBL19624677 0.91 FFAR4 (0.41) FFAR4FFAR1PTGER4
SCHEMBL19804021 0.87 FFAR4 (0.40) FFAR4FFAR1PTGER4MAP2K4THRB
SCHEMBL19624460 0.85 FFAR4 (0.43) FFAR4FFAR1PTGER4THRBMAPK1
SCHEMBL19796432 0.85 THRB (0.48) FFAR4FFAR1PTGER4THRBALOX5
SCHEMBL19796374 0.84 THRB (0.50) FFAR4FFAR1THRBMEN1KMT2A
SCHEMBL19804346 0.83 FFAR4 (0.40) FFAR4FFAR1PTGER4MAP2K4BAZ2B
SCHEMBL19804679 0.83 FFAR1 (0.41) FFAR4FFAR1PTGER4THRBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180023001-A1 COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180023001-A1 COMPOUND HAVING POLYMERIZABLE GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, C1S, AP3D1 FFAR4 1715/4885FFAR1 1057/4885PTGER4 2215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.