Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 12/20 | 0.53 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22912302 | 0.89 | SDHB (0.54) | SDHBPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21019932 | 0.87 | SDHB (0.58) | SDHBPTGDRPDE4APDE4BPDE4C | |
| SCHEMBL29976590 | 0.87 | SDHB (0.71) | SDHB | |
| SCHEMBL20985740 | 0.87 | SDHB (0.71) | SDHB | |
| SCHEMBL26313101 | 0.84 | SDHB (0.56) | SDHBPTGDRPDE4APDE4BPDE4C | |
| SCHEMBL19806091 | 0.83 | SDHB (0.55) | SDHBPTGDRPDE4APDE4BPDE4C | |
| SCHEMBL19805843 | 0.83 | SDHB (0.55) | SDHBPTGDRPDE4APDE4BPDE4C | |
| SCHEMBL23897424 | 0.82 | SDHB (0.64) | SDHB | |
| SCHEMBL21019928 | 0.81 | SDHB (0.53) | SDHBPTGDRPDE4APDE4BPDE4C | |
| SCHEMBL19806124 | 0.81 | SDHB (0.49) | SDHBPTGDRPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018014802-A1 | APOPTOSIS INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-01-25 | — | — | WO | disclosed |