⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13255133 | 1.00 | — | — | |
| SCHEMBL1266170 | 1.00 | — | — | |
| SCHEMBL5242956 | 0.85 | CA1 (0.30) | — | |
| SCHEMBL8206110 | 0.83 | — | — | |
| SCHEMBL3440805 | 0.83 | CA1 (0.43) | — | |
| SCHEMBL3224313 | 0.77 | CA1 (0.32) | — | |
| SCHEMBL15957272 | 0.77 | CA1 (0.32) | — | |
| SCHEMBL21995884 | 0.76 | SLC6A3 (0.33) | — | |
| SCHEMBL11317051 | 0.76 | — | — | |
| SCHEMBL3537331 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10399994-B2 | Compounds and methods for preventing or treating sensory hair cell death | UNIVERSITY OF WASHINGTON (US) | 2019-09-03 | — | — | US | disclosed |
| US-20180022756-A1 | COMPOUNDS AND METHODS FOR PREVENTING OR TREATING SENSORY HAIR CELL DEATH | FRED HUTCHINSON CANCER CENTER | 2018-01-25 | — | — | US | disclosed |